D-Ryboza - cudowny dodatek do kreatyny?........KIT!

Czesto widzimi takie stwierdzenia:

'......
D-ryboza i kreatyna rewelacyjnie współdziałają, jednak nie należy sądzić, że suplementacja samej rybozy jest nieskuteczna. Stosowana sama działa podobnie do kreatyny (rozwija masę, siłę, szybkość i wytrzymałość), z tym, że średnio 3-krotnie skuteczniej.

Ponieważ organizm pewną ilość kreatyny i rybozy wytwarza samodzielnie, oddzielne zastosowanie kreatyny lub rybozy "zaprzęga" do współpracy pulę drugiej substancji wytworzoną przez organizm. Jednak wtedy efektywność wspomagania ograniczona jest zasobnością tej puli. To tłumaczy, dlaczego sama kreatyna działa dużo słabiej, niż w połączeniu z D-rybozą.
.....'

Kilka ciekawych badan:

No effects of oral ribose supplementation on repeated maximal exercise and de novo ATP resynthesis.

A double-blind randomized study was performed to evaluate the effect of oral ribose supplementation on repeated maximal exercise and ATP recovery after intermittent maximal muscle contractions. Muscle power output was measured during dynamic knee extensions with the right leg on an isokinetic dynamometer before (pretest) and after (posttest) a 6-day training period in conjunction with ribose (R, 4 doses/day at 4 g/dose, n = 10) or placebo (P, n = 9) intake. The exercise protocol consisted of two bouts (A and B) of maximal contractions, separated by 15 s of rest. Bouts A and B consisted of 15 series of 12 contractions each, separated by a 60-min rest period. During the training period, the subjects performed the same exercise protocol twice per day, with 3-5 h of rest between exercise sessions. Blood samples were collected before and after bouts A and B and 24 h after bout B. Knee-extension power outputs were approximately 10% higher in the posttest than in the pretest but were similar between P and R for all contraction series. The exercise increased blood lactate and plasma ammonia concentrations (P < 0.05), with no significant differences between P and R at any time. After a 6-wk washout period, in a subgroup of subjects (n = 8), needle-biopsy samples were taken from the vastus lateralis before, immediately after, and 24 h after an exercise bout similar to the pretest. ATP and total adenine nucleotide content were decreased by approximately 25 and 20% immediately after and 24 h after exercise in P and R. Oral ribose supplementation with 4-g doses four times a day does not beneficially impact on postexercise muscle ATP recovery and maximal intermittent exercise performance.

http://www.ncbi.nlm.nih.gov/pubmed/11641371

suplementacja ryboza w ilosci 4g 4x/dzien (16g/dzien) w porownaniu do grupy placebo nie wykazala zadnych istotnych roznic w poziomie ATP jak i w polepszeniu wykonania treningu


Effects of ribose supplementation on repeated sprint performance in men

This study used a randomized, placebo-controlled, crossover design to evaluate the effects of oral ribose supplementation on short-term anaerobic performance. After familiarization, subjects performed 2 bouts of repeated cycle sprint exercise (six 10-second sprints with 60-second rest periods between sprints) in a single day. After the second exercise, bout subjects ingested 32 g of ribose or cellulose (4 x 8-g doses) during the next 36 hours. After supplementation, subjects returned to the laboratory to perform a single bout of cycle sprinting (as described above). After a 5-day washout period, subjects repeated the protocol, receiving the opposite supplement treatment. Ribose supplementation lead to statistically significant increases in mean power and peak power in sprint 2 (10.9 and 6.6%, respectively) and higher (although not significant) absolute values in sprints 1, 3, and 4. In conclusion, ribose supplementation did not show reproducible increases in performance across all 6 sprints. Therefore, within the framework of this investigation, it appears that ribose supplementation does not have a consistent or substantial effect on anaerobic cycle sprinting.

http://www.ncbi.nlm.nih.gov/pubmed/12580655

2grupy
-grupa placebo
-grupa spozywajaca d-ryboze (32g)

wnisoki:
suplementacja d-ryboza nie wykazala zadnych (znaczacych) roznic - jesli chodzi o poprawienie osiągów


Effects of oral D-ribose supplementation on anaerobic capacity and selected metabolic markers in healthy males.

Oral D-ribose supplementation has been reported to increase adenine nucleotide synthesis and exercise capacity in certain clinical populations. Theoretically, increasing adenine nucleotide availability may enhance high intensity exercise capacity. This study evaluated the potential ergogenic value of D-ribose supplementation on repetitive high-intensity exercise capacity in 19 trained males. Subjects were familiarized to the testing protocol and performed two practice-testing trials before pre-supplementation testing. Each test involved warming up for 5 min on a cycle ergometer and then performing two 30-s Wingate anaerobic sprint tests on a computerized cycle ergometer separated by 3 min of rest recovery. In the pre- and post-supplementation trials, blood samples were obtained at rest, immediately following the first and second sprints, and following 5 min of recovery from exercise. Subjects were then matched according to body mass and anaerobic capacity and assigned to ingest, in a randomized and double blind manner, capsules containing either 5 g of a dextrose placebo (P) or D-ribose (R) twice daily (10 g/d) for 5 d. Subjects then performed post-supplementation tests on the 6th day. Data were analyzed by ANOVA for repeated measures. Results revealed a significant interaction (p =.04) in total work output. Post hoc analysis revealed that work significantly declined (-18 +/- 51 J) during the second post-supplementation sprint in the P group while being maintained in the R group (-0.0 +/- 31 J). No significant interactions were observed in peak power, average power, torque, fatigue index, lactate, ammonia, glucose, or uric acid. Results indicate that oral ribose supplementation (10 g/d for 5 d) does not affect anaerobic exercise capacity or metabolic markers in trained subjects as evaluated in this study.

http://www.ncbi.nlm.nih.gov/pubmed/12660407

dwie grupy:
-placebo
-grupa przyjmujaca 5g d-rybozy 2x dziennie (10g) przez 5 dni

wnioski:
nie odnotowano istotnych roznic pomiedzy grupa placebo o grupa przyjmujaca d-ryboze jesli chodzi o takie parametry jak:
-moc szczytowa
-srednia moc
-zmeczenie

d-ryboza nie poprawiloa osiagow w wysilku beztlenowym


Effects of ribose supplementation prior to and during intense exercise on anaerobic capacity and metabolic markers.

This study examined whether ribose supplementation before and during intense anaerobic exercise impacts anaerobic capacity and metabolic markers. Twelve moderately trained male cyclists (22.3 +/- 2.2 y; 181 +/- 6 cm, 74.8 +/- 9 kg) participated in the study. Subjects were familiarized and fasted for 8 h after standardizing nutritional intake. In a double blind and crossover manner subjects ingested either a 150 mL placebo or ribose (3 g ribose + 150 microg folate). Subjects rested for 25 min and completed 5 x 30 s anaerobic capacity tests with 3 min passive rest. Six capillary blood samples were taken prior to and after sprints for adenine nucleotide breakdown determination. The experiment was repeated 1 wk later with alternative drink. Data were analyzed by repeated measures ANOVA. No significant interactions were observed for any performance or blood variables. D-ribose supplementation has no impact on anaerobic exercise capacity and metabolic markers after high-intensity cycling exercise.

http://www.ncbi.nlm.nih.gov/pubmed/16521849

dwie grupy:
-placebo spozywajaca 150ml plynu
-grupa spozywajaca 3g rybozy + 150ml plynu

wnioski:
nie odnotowano zadnych roznic w poprawieniu osiagow podczas wysilku beztlenowego



Na koniec ciekawe badanie - ryboza vs dextroza:

Ribose versus dextrose supplementation, association with rowing performance: a double-blind study.

OBJECTIVE: It has been hypothesized that ribose supplementation rapidly replenishes adenosine triphosphate stores and thereby improves exercise performance. We compared the effects of ribose versus dextrose on rowing performance.

DESIGN: Double-blind randomized trial.

SETTING: Rowing team training area of large midwestern university.

PARTICIPANTS: Thirty-one women collegiate rowers.

INTERVENTIONS: We studied the effects of ribose versus dextrose supplementation (10 g each in 8 oz water) for 8 weeks before and after practice and 2000-m time trials. OUTCOME MEASUREMENTS AND RESULTS: In the time trials, the dextrose group showed significantly more improvement at 8 weeks than the ribose group (median, 15.2 vs. 5.2 s; P = 0.031).

CONCLUSIONS: We doubt ribose impaired, and hypothesize dextrose enhanced, rowing performance. Further research is needed to define what role, if any, dextrose and ribose play as athletic supplements.

http://www.ncbi.nlm.nih.gov/pubmed/16377979

32wioślarki spozywajace prze 8 tygodni:
-10g dextrozy
lub
-10g rybozy

wnioski:
czas pokanania 2000m (po 8 tygodniach) byl szybszy w grupie przyjmujacej dextroze - 15,2 sekundy szybciej - niz w grupie przyjmujacej ryboze - 5,2 sekundy szybciej


....wniosek nasuwa sie tylko jeden.


Zmieniony przez - solaros w dniu 2011-02-09 01:28:19

Wiadomo od dawna, ale dzieki za opracowanie.

....wniosek nasuwa sie tylko jeden:

kreatyna + dextroza + ryboza

Taa, chyba 10 lat temu...

Do kreatyny nie należy stosować żadnych dodatków, mają znikomy wpływ. Jeśli już to białka + węgle.

Carbohydrates:
In humans, absorption of creatine appears to be enhanced by concurrent carbohydrate ingestion. In a randomized, controlled trial, post-exercise supplementation with carbohydrate and creatine results in similar strength gains as protein and carbohydrate. In humans, ingesting creatine with carbohydrates augmented glycogen supercompensation in exercised muscle.

McNaughton, L. R., Dalton, B., and Tarr, J. The effects of creatine supplementation on high-intensity exercise performance in elite performers. Eur.J Appl.Physiol Occup.Physiol 1998;78(3):236-240.

Green, A. L., Hultman, E., Macdonald, I. A., Sewell, D. A., and Greenhaff, P. L. Carbohydrate ingestion augments skeletal muscle creatine accumulation during creatine supplementation in humans. Am.J Physiol 1996;271(5 Pt 1):E821-E826.

Green, A. L., Simpson, E. J., Littlewood, J. J., Macdonald, I. A., and Greenhaff, P. L. Carbohydrate ingestion augments creatine retention during creatine feeding in humans. Acta Physiol Scand 1996;158(2):195-202.

Preen, D., Dawson, B., Goodman, C., Beilby, J., and Ching, S. Creatine supplementation: a comparison of loading and maintenance protocols on creatine uptake by human skeletal muscle. Int J Sport Nutr.Exerc.Metab 2003;13(1):97-111.

Tarnopolsky, M. A., Parise, G., Yardley, N. J., Ballantyne, C. S., Olatinji, S., and Phillips, S. M. Creatine-dextrose and protein-dextrose induce similar strength gains during training. Med Sci Sports Exerc 2001;33(12):2044-2052.

Robinson, T. M., Sewell, D. A., Hultman, E., and Greenhaff, P. L. Role of submaximal exercise in promoting creatine and glycogen accumulation in human skeletal muscle. J Appl.Physiol 1999;87(2):598-604.

gdzie tu jest cos o d-rybozie?